Gephyrin anticorps (AA 231-330)
Aperçu rapide pour Gephyrin anticorps (AA 231-330) (ABIN719321)
Antigène
Voir toutes Gephyrin (GPHN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 231-330
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Réactivité croisée
- Souris
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Homologie
- Human,Rat,Dog,Cow,Pig,Horse,Rabbit
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Purification
- Purified by Protein A.
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Immunogène
- KLH conjugated synthetic peptide derived from human Gephyrin
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Isotype
- IgG
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Indications d'application
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Date de péremption
- 12 months
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- Gephyrin (GPHN)
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Autre désignation
- Gephyrin
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Sujet
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Synonyms: Domain E, Domain G, GEPH, GEPH_HUMAN, GPH, GPHN, GPHRYN, Molybdopterin molybdenumtransferase, MPT adenylyltransferase, MPT Mo-transferase.
Background: The sub-membraneous region at the postsynaptic membrane contains a number of proteins critical for receptor targeting. Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.
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ID gène
- 10243
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Pathways
- Synaptic Membrane, Skeletal Muscle Fiber Development
Antigène
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