IFNGR1 anticorps (APC)

N° du produit ABIN7456467

Cet anticorps Rat Monoclonal détecte spécifiquement IFNGR1 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour IFNGR1 anticorps (APC) (ABIN7456467)

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNGR1 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: GR-20

Détail du produit anti-IFNGR1 anticorps (APC)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: APC Rat IgG2a, κ Isotype Control (ABIN7469841)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur IFNGR1

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Autre désignation: CD119

Sujet: Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119,CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

ID gène: 15979

UniProt: P15261

Pathways: Interferon-gamma Pathway