Endoglin anticorps (APC)

N° du produit ABIN7456580

Cet anticorps anti-Endoglin est un anticorps Rat Monoclonal détectant Endoglin dans FACS. Adapté pour Souris.

Aperçu rapide pour Endoglin anticorps (APC) (ABIN7456580)

Antigène: Endoglin (ENG)

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Endoglin est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: MJ7-18

Détail du produit anti-Endoglin anticorps (APC)

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: APC Rat IgG2a, κ Isotype Control (ABIN7469841)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur Endoglin

Antigène: Endoglin (ENG)

Autre désignation: CD105

Sujet: Endoglin,END,Eng,CD105 is a 90 kD homodimeric type I integral membrane glycoprotein, also known as endoglin. It is expressed on endothelial cells (especially on angiogenic endothelial cells) and upregulated by hypoxia, activated monocytes, macrophages, bone marrow stromal cells, and some cytotrophoblasts. CD105 is a receptor for TGF-β1, TGF-β3 and modulates TGF-β signaling by interacting with TGF-β receptors I and/or II. CD105 also binds other growth factors such as actvin A, BMP-2, and BMP-7. CD105 has been show to be a useful marker for identifying proliferating endothelium involved in tumor angiogenesis and can be used for tumor imaging and prognosis, and has therapeutic potential for some solid tumors and other angiogenic diseases.

ID gène: 13805

UniProt: Q63961