CD163 anticorps (APC)
Aperçu rapide pour CD163 anticorps (APC) (ABIN7456603)
Antigène
Voir toutes CD163 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Isotype
- IgG2a, kappa
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Indications d'application
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
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Commentaires
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Matching Isotype Control: APC Rat IgG2a, κ Isotype Control[2A3] (ABIN7469841)
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Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.05 % Proclin300, 1 % Protein protectant
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- CD163
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Autre désignation
- CD163
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Sujet
- M130, MM130, SCARI1,CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.
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ID gène
- 93671
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UniProt
- Q2VLH6
Antigène
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