CD51 anticorps (Biotin)

N° du produit ABIN7456695

Cet anticorps Rat Monoclonal détecte spécifiquement CD51 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD51 anticorps (Biotin) (ABIN7456695)

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Clone: RMV-7

Détail du produit anti-CD51 anticorps (Biotin)

Isotype: IgG1, kappa

Information d'application

Indications d'application: For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Commentaires:

Matching Isotype Control: Biotin Rat IgG1, κ Isotype Control (ABIN7469820)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C. Do not freeze.

Détails sur CD51

Antigène: CD51 (ITGAV) (Integrin alpha V (ITGAV))

Autre désignation: CD51

Sujet: Integrin alpha-V,αV integrin,Vitronectin Receptor,Integrin αV chain,ITGAV,CD51 is a 140 kD protein, also known as αV integrin, vitronectin receptor, and integrin αV. It is a member of the integrin family, expressed on activated T cells, polymorphonuclear granulocytes, platelets, blastocysts, and osteoclasts. CD51 forms heterodimers by association with integrins β1, β3, β5 or β6, these complexes then act as receptors for multiple extracellular matrix proteins (ECM). The αvintegrin heterodimers have varied functions in development, stimulation/activation and homeostasis. The primary ligands for CD51 complexes are fibronectin, fibrinogen, vitronectin, thrombspondin, von Willebrand factor, and CD31. The RMV-7 antibody has been reported to block binding of CD51 to vitronectin, fibronectin, and CD31 in some cell types, as well as blocking LAK cell cytotoxicity.

ID gène: 16410

UniProt: P43406

Pathways: Cell-Cell Junction Organization, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Integrin Complex