PD-1 anticorps (FITC)

N° du produit ABIN7456906

L’anticorps Souris Monoclonal anti-PD-1 a été validé pour FACS. Il convient pour détecter PD-1 dans des échantillons de Humain.

Aperçu rapide pour PD-1 anticorps (FITC) (ABIN7456906)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: EH12-2H7

Détail du produit anti-PD-1 anticorps (FITC)

Isotype: IgG1, kappa

Information d'application

Indications d'application: The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Commentaires:

Matching Isotype Control: FITC Mouse IgG1, κ Isotype Control (ABIN7469760)

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: CD279/PD-1

Sujet: PDCD1,PD1,Protein PD-1,hPD-1,Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.

ID gène: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints