Interleukin 17a anticorps (PE)

N° du produit ABIN7457144

Cet anticorps anti-Interleukin 17a est un anticorps Rat Monoclonal détectant Interleukin 17a dans ICFC. Adapté pour Souris.

Aperçu rapide pour Interleukin 17a anticorps (PE) (ABIN7457144)

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp Interleukin 17a est conjugé à/à la PE

Application: Intracellular Flow Cytometry (ICFC)

Clone: TC11-18H10-1

Détail du produit anti-Interleukin 17a anticorps (PE)

Isotype: IgG1, kappa

Information d'application

Indications d'application: Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].

Commentaires:

Matching Isotype Control: PE Rat IgG1, κ Isotype Control (ABIN7469822)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Détails sur Interleukin 17a

Antigène: Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

Autre désignation: IL-17A

Sujet: Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,CTLA8,IL-17, also known as CTLA-8, is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpes virus Saimiri. IL-17 is produced by Th cells (Th17) that are distinct from the traditional Th1- and Th2-cell subsets. IL-23 plays an important role in triggering IL-17 production. Both recombinant and natural IL-17 have been shown to exist as disulfide linked homodimers. IL-17 exhibits multiple biological activities on a variety of cells including: the induction of IL-6 and IL-8 production in fibroblasts, activation of NF-κB, and costimulation of T cell proliferation. IL-17 is an essential inflammatory mediator in the development of autoimmune diseases. Neutralization of IL-17 with monoclonal antibody is able to ameliorate the disease course.

ID gène: 16171

UniProt: Q62386