IFNGR1 anticorps

N° du produit ABIN7457947

L’anticorps Rat Monoclonal anti-IFNGR1 a été validé pour FACS. Il convient pour détecter IFNGR1 dans des échantillons de Souris.

Aperçu rapide pour IFNGR1 anticorps (ABIN7457947)

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNGR1 est non-conjugé

Application: Flow Cytometry (FACS)

Clone: GR-20

Détail du produit anti-IFNGR1 anticorps

Purification: Purified

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Matching Isotype Control: AF/LE Purified Rat IgG2a, κ Isotype Control (ABIN7469836)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store at 2~8°C. Do not freeze.

Détails sur IFNGR1

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Autre désignation: CD119

Sujet: Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119,CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

ID gène: 15979

UniProt: P15261

Pathways: Interferon-gamma Pathway