IFNGR1 anticorps
Aperçu rapide pour IFNGR1 anticorps (ABIN7457948)
Antigène
Voir toutes IFNGR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Purification
- Purified
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Isotype
- IgG2a, kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Matching Isotype Control: Purified Rat IgG2a, κ Isotype Control (ABIN7469837)
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- PBS with 0.05 % Proclin300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2~8°C. Do not freeze.
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- IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))
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Autre désignation
- CD119
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Sujet
- Interferon gamma receptor 1,Ifngr1,IFN-gamma-R1,IFN-gamma-R-alpha,CD119,CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.
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ID gène
- 15979
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UniProt
- P15261
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Pathways
- Interferon-gamma Pathway
Antigène
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