TIM3 anticorps

N° du produit ABIN7457965

L’anticorps anti-TIM3 Monoclonal Rat est utilisé pour la détection de TIM3 dans des échantillons de Souris. Il a été validé pour FACS et BR.

Aperçu rapide pour TIM3 anticorps (ABIN7457965)

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TIM3 est non-conjugé

Application: Flow Cytometry (FACS), Blocking Reagent (BR)

Clone: RMT3-23

Détail du produit anti-TIM3 anticorps

Purification: Purified

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Low Endotoxin: Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Matching Isotype Control: AF/LE Purified Rat IgG2a, κ Isotype Control (ABIN7469836)

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE)

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store at 2~8°C. Do not freeze.

Détails sur TIM3

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Autre désignation: CD366/Tim-3

Classe de substances: Virus

Sujet: TIM3, TIMD3,HAVcr-2,TIMD-3,CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.

ID gène: 84868

UniProt: Q8VIM0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints