STEAP3 anticorps
Aperçu rapide pour STEAP3 anticorps (ABIN7464576)
Antigène
Voir toutes STEAP3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée
- Humain
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Purification
- Purified by antigen-affinity chromatography.
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Immunogène
- Recombinant protein encompassing a sequence within the center region of human STEAP3. The exact sequence is proprietary.
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Isotype
- IgG
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Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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Commentaires
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Positive Control: HepG2 cytoplasm extract
Validation: Orthogonal
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.79 mg/mL
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Buffer
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
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Agent conservateur
- ProClin
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Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
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Autre désignation
- STEAP3 metalloreductase
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Sujet
- STEAP3 metalloreductase , AHMIO2 , STMP3 , TSAP6 , dudlin-2 , dudulin-2 , pH yde,Endosomal ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Participates in erythroid iron homeostasis by reducing Fe(3+) to Fe(2+). Can also reduce of Cu(2+) to Cu(1+), suggesting that it participates in copper homeostasis. Uses NAD(+) as acceptor (By similarity). May play a role downstream of p53/TP53 to interface apoptosis and cell cycle progression. Indirectly involved in exosome secretion by facilitating the secretion of proteins such as TCTP.
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Poids moléculaire
- 55 kDa
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ID gène
- 55240
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UniProt
- Q658P3
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Pathways
- Transition Metal Ion Homeostasis
Antigène
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