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Rhotekin anticorps (N-Term)

Cet anticorps anti-Rhotekin est un anticorps Lapin Polyclonal détectant Rhotekin dans WB, IF et ICC. Adapté pour Humain.
N° du produit ABIN7464752

Aperçu rapide pour Rhotekin anticorps (N-Term) (ABIN7464752)

Antigène

Voir toutes Rhotekin (RTKN) Anticorps
Rhotekin (RTKN)

Reactivité

  • 26
  • 8
  • 8
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
Humain

Hôte

  • 23
  • 5
Lapin

Clonalité

  • 24
  • 4
Polyclonal

Conjugué

  • 21
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Rhotekin est non-conjugé

Application

  • 20
  • 12
  • 7
  • 5
  • 5
  • 4
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • Épitope

    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

     Réactivité croisée

    Humain, Souris

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the N-terminus region of human Rhotekin. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: Mouse brain , Jurkat , Raji , NCI-H929 , human Rhotekin-transfected 293T cells

    Validation: Overexpression

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    0.54 mg/mL

    Buffer

    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    Rhotekin (RTKN)

    Autre désignation

    rhotekin

    Sujet

    Rhotekin,This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

    Poids moléculaire

    63 kDa

    ID gène

    6242

    UniProt

    Q9BST9
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