SHANK1 anticorps (C-Term)

N° du produit ABIN7465113

Cet anticorps Lapin Polyclonal détecte spécifiquement SHANK1 dans WB, ICC, IF, IHC (fro) et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour SHANK1 anticorps (C-Term) (ABIN7465113)

Antigène: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHANK1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-SHANK1 anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human SHANK1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.53 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur SHANK1

Antigène: SHANK1 (SH3 and Multiple Ankyrin Repeat Domains 1 (SHANK1))

Autre désignation: SH3 and multiple ankyrin repeat domains 1

Sujet: SH3 and multiple ankyrin repeat domains 1 , SPANK-1 , SSTRIP , synamon,Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors via complexes with GKAP/PSD-95 and Homer, respectively, and the actin-based cytoskeleton. May play a role in the structural and functional organization of the dendritic spine and synaptic junction.

Poids moléculaire: 225 kDa

ID gène: 50944

UniProt: Q9Y566

Pathways: Synaptic Membrane, Maintenance of Protein Location