MIP anticorps (PE)

N° du produit ABIN719586

Cet anticorps anti-MIP est un anticorps Lapin Polyclonal détectant MIP dans IF (p). Adapté pour Humain, Souris, Rat, Cobaye, Porc, Poulet et Boeuf (Vache).

Aperçu rapide pour MIP anticorps (PE) (ABIN719586)

Antigène: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Reactivité: Humain, Souris, Rat, Cobaye, Porc, Poulet, Boeuf (Vache)

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MIP est conjugé à/à la PE

Application: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-MIP anticorps (PE)

Specificité: Excitation / Emission Wavelengths: 565nm/578nm

Réactivité croisée: Rat (Rattus), Poulet, Porc, Boeuf (Vache), Cobaye

Purification: purified by Protein A

Immunogène: KLH conjugated synthetic peptide derived from human AQP0

Isotype: IgG

Information d'application

Commentaires:

Excitation / Emission wavelength: 496nm / 578nm

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 4 °C for 12 months

Date de péremption: 12 months

Détails sur MIP

Antigène: MIP (Major Intrinsic Protein of Lens Fiber (MIP))

Autre désignation: AQP0

Sujet: Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein aquaporins. Aquaporin 0 or MIP26 (major intrinsic protein 26kD), and Aquaporin 1 has been the foundation of the growing family of aquaporins. The lens specific Aquaporin 0 represents up to 80% of total lens membrane protein. Defects in Aquaporin 0 are a cause of autosomal recessive congenital cataract. The lens opacity mutation (LOP) is an AA substitution that inhibits targeting of MIP to the cell membrane. Human Aquaporin 0 is a 263 amino acid transmembrane protein belonging to the MIP family. Aquaporin families of proteins are predicted to contain six transmembrane domains. The N and C terminus are predicted to be cytoplasmic.

Poids moléculaire: 28kDa

ID gène: 4284