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THOC7 anticorps

Cet anticorps anti-THOC7 est un anticorps Lapin Polyclonal détectant THOC7 dans WB, ICC et IF. Adapté pour Humain.
N° du produit ABIN7465253

Aperçu rapide pour THOC7 anticorps (ABIN7465253)

Antigène

Voir toutes THOC7 Anticorps
THOC7 (THO Complex 7 (THOC7))

Reactivité

  • 22
  • 13
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
Humain

Hôte

  • 22
Lapin

Clonalité

  • 22
Polyclonal

Conjugué

  • 11
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp THOC7 est non-conjugé

Application

  • 10
  • 6
  • 2
  • 2
  • 1
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
  •  Réactivité croisée

    Humain, Souris

    Purification

    Purified by antigen-affinity chromatography.

    Immunogène

    Recombinant protein encompassing a sequence within the center region of human THOC7. The exact sequence is proprietary.

    Isotype

    IgG
  • Indications d'application

    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    Commentaires

    Positive Control: 293T , A431 , Mouse brain

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

    Agent conservateur

    Thimerosal (Merthiolate)

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Antigène

    THOC7 (THO Complex 7 (THOC7))

    Autre désignation

    THO complex 7

    Sujet

    THO complex 7 , NIF3L1BP1 , fSAP24 , hTREX30,Component of the THO subcomplex of the TREX complex. The TREX complex specifically associates with spliced mRNA and not with unspliced pre-mRNA. It is recruited to spliced mRNAs by a transcription-independent mechanism. Binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export. The recruitment occurs via an interaction between THOC4 and the cap-binding protein NCBP1. UAP56 functions as a bridge between THOC4 and the THO complex. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus (KSHV) intronless mRNAs and infectious virus production. The recruitment of the TREX complex to the intronless viral mRNA occurs via an interaction between KSHV ORF57 protein and THOC4.

    Poids moléculaire

    24 kDa

    ID gène

    80145

    UniProt

    Q6I9Y2
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