Amylin/DAP anticorps (C-Term)

N° du produit ABIN7465641

Cet anticorps Lapin Polyclonal détecte spécifiquement Amylin/DAP dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Amylin/DAP anticorps (C-Term) (ABIN7465641)

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Amylin/DAP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Amylin/DAP anticorps

Épitope: C-Term

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Amylin. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: AsPC1

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.83 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Amylin/DAP

Antigène: Amylin/DAP (IAPP) (Islet Amyloid Polypeptide (IAPP))

Autre désignation: islet amyloid polypeptide

Sujet: Islet amyloid polypeptide , DAP , IAP,Islet, or insulinoma, amyloid polypeptide is commonly found in pancreatic islets of patients suffering diabetes mellitus type II, or harboring an insulinoma. While the assosciation of amylin with the development of type II diabetes has been known for some time, a direct causative role for amylin has been harder to establish. Studies suggest that amylin, like the related beta-amyloid (Abeta) associated with Alzheimer's disease, can induce apoptotic cell-death in particular cultured cells, an effect that may be relevant to the development of type II diabetes. [provided by RefSeq]

Poids moléculaire: 10 kDa

ID gène: 3375

UniProt: P10997

Pathways: Hormone Activity, Feeding Behaviour