Coagulation Factor X anticorps

N° du produit ABIN7466218

L’anticorps Souris Monoclonal anti-Coagulation Factor X a été validé pour WB, ICC et IF. Il convient pour détecter Coagulation Factor X dans des échantillons de Humain.

Aperçu rapide pour Coagulation Factor X anticorps (ABIN7466218)

Antigène: Coagulation Factor X (F10)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Coagulation Factor X est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Clone: GT268

Détail du produit anti-Coagulation Factor X anticorps

Réactivité croisée: Humain

Purification: Affinity purified by Protein G.

Immunogène: Recombinant protein encompassing a sequence within the center region of human Factor X. The exact sequence is proprietary.

Isotype: IgG2b

Information d'application

Indications d'application: WB: 1:5000-1:20000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: human F10-transfected 293T cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS, No Preservative

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur Coagulation Factor X

Antigène: Coagulation Factor X (F10)

Autre désignation: coagulation factor X

Sujet: Coagulation factor X , FX , FXA,This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds, the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. [provided by RefSeq]

Poids moléculaire: 55 kDa

ID gène: 2159

UniProt: P00742