DHCR7 anticorps (C-Term)

N° du produit ABIN7466581

L’anticorps Lapin Polyclonal anti-DHCR7 a été validé pour WB et IHC (p). Il convient pour détecter DHCR7 dans des échantillons de Humain.

Aperçu rapide pour DHCR7 anticorps (C-Term) (ABIN7466581)

Antigène: DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DHCR7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Détail du produit anti-DHCR7 anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human DHCR7. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.86 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur DHCR7

Antigène: DHCR7 (7-Dehydrocholesterol Reductase (DHCR7))

Autre désignation: 7-dehydrocholesterol reductase

Sujet: 7-dehydrocholesterol reductase , SLOS,The DHCR7 gene encodes delta-7-sterol reductase (EC 1.3.1.21), the penultimate enzyme of mammalian sterol biosynthesis that converts 7-dehydrocholesterol (7-DHC) to cholesterol. This enzyme removes the C(7-8) double bond introduced by the sterol delta8-delta7 isomerases. In addition, its role in drug-induced malformations is known: inhibitors of the last step of cholesterol biosynthesis such as AY9944 and BM15766 severely impair brain development (Moebius et al., 1998 [PubMed 9465114]).[supplied by OMIM]

Poids moléculaire: 54 kDa

ID gène: 1717

UniProt: Q9UBM7