LIM Domain Binding 3 Protein anticorps

N° du produit ABIN7467111

Cet anticorps Lapin Polyclonal détecte spécifiquement LIM Domain Binding 3 Protein dans WB et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour LIM Domain Binding 3 Protein anticorps (ABIN7467111)

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LIM Domain Binding 3 Protein est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-LIM Domain Binding 3 Protein anticorps

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human LDB3. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: NT2D1 , RD , rat muscle , mouse muscle

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur LIM Domain Binding 3 Protein

Antigène: LIM Domain Binding 3 Protein (LDB3) (LIM Domain Binding 3 (LDB3))

Autre désignation: LIM domain binding 3

Sujet: LIM domain binding 3 , CMD1C , CMH24 , CMPD3 , CYPHER , LDB3Z1 , LDB3Z4 , LVNC3 , MFM4 , ORACLE , PDLIM6 , ZASP,This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified, all isoforms have N-terminal PDZ domains while only longer isoforms (1 and 2) have C-terminal LIM domains. [provided by RefSeq]

Poids moléculaire: 77 kDa

ID gène: 11155

UniProt: O75112