BAIAP2 anticorps
Aperçu rapide pour BAIAP2 anticorps (ABIN7467418)
Antigène
Voir toutes BAIAP2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Réactivité croisée
- Humain, Souris, Rat
-
Purification
- Purified by antigen-affinity chromatography.
-
Immunogène
- Recombinant protein encompassing a sequence within the center region of human BAIAP2. The exact sequence is proprietary.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- WB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Commentaires
-
Positive Control: SK-N-SH , mouse brain , rat brain
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.7 mg/mL
-
Buffer
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
-
Agent conservateur
- Thimerosal (Merthiolate)
-
Précaution d'utilisation
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- BAIAP2 (BAI1-Associated Protein 2 (BAIAP2))
-
Autre désignation
- BAI1 associated protein 2
-
Sujet
- BAI1 associated protein 2 , BAP2 , FLAF3 , IRSP53,The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
-
Poids moléculaire
- 61 kDa
-
ID gène
- 10458
-
UniProt
- Q9UQB8
Antigène
-