IVNS1ABP anticorps (C-Term)

N° du produit ABIN7467508

L’anticorps Lapin Polyclonal anti-IVNS1ABP a été validé pour WB et IHC (p). Il convient pour détecter IVNS1ABP dans des échantillons de Humain.

Aperçu rapide pour IVNS1ABP anticorps (C-Term) (ABIN7467508)

Antigène: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IVNS1ABP est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IVNS1ABP anticorps

Épitope: C-Term

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human IVNS1ABP. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: U87-MG

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.57 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur IVNS1ABP

Antigène: IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))

Autre désignation: influenza virus NS1A binding protein

Classe de substances: Influenza Protein

Sujet: Influenza virus NS1A binding protein , ARA3 , FLARA3 , HSPC068 , KLHL39 , ND1 , NS-1 , NS1-BP , NS1BP,Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization, Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing, may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

Poids moléculaire: 72 kDa

ID gène: 10625

UniProt: Q9Y6Y0

Pathways: Negative Regulation of intrinsic apoptotic Signaling