Splicing factor U2AF 26 kDa subunit (U2AF1L4) anticorps

N° du produit ABIN7467804

Cet anticorps Lapin Polyclonal détecte spécifiquement dans IF et ICC. Il présente une réactivité envers Humain.

Aperçu rapide pour Splicing factor U2AF 26 kDa subunit (U2AF1L4) anticorps (ABIN7467804)

Antigène: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human U2AF1L4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détail du antigène

Antigène: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Autre désignation: U2 small nuclear RNA auxiliary factor 1 like 4

Sujet: U2 small nuclear RNA auxiliary factor 1 like 4 , U2AF1-RS3 , U2AF1L3 , U2AF1L3V1 , U2AF1RS3 , U2af26,RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site.

Poids moléculaire: 22 kDa

ID gène: 199746

UniProt: Q8WU68