Splicing factor U2AF 26 kDa subunit (U2AF1L4) anticorps

N° du produit ABIN7467804

Détail du produit

Antigène: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunofluorescence (IF), Immunocytochemistry (ICC)

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human U2AF1L4. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détail du antigène

Antigène: Splicing factor U2AF 26 kDa subunit (U2AF1L4)

Autre désignation: U2 small nuclear RNA auxiliary factor 1 like 4 (U2AF1L4 Produits)

Synonymes: anticorps U2 small nuclear RNA auxiliary factor 1-like protein 3, anticorps U2AF1-RS3, anticorps U2AF1-like 4, anticorps U2AF1-like protein 3, anticorps U2AF1L3, anticorps U2AF1L3V1, anticorps U2AF1RS3, anticorps U2af26, anticorps AA407033, anticorps AF419339, anticorps AI451269, anticorps AW553050, anticorps TMEM149, anticorps U2 small nuclear RNA auxiliary factor 1 like 4, anticorps U2 small nuclear RNA auxiliary factor 1-like 4, anticorps U2AF1L4, anticorps U2af1l4

Sujet: U2 small nuclear RNA auxiliary factor 1 like 4 , U2AF1-RS3 , U2AF1L3 , U2AF1L3V1 , U2AF1RS3 , U2af26,RNA-binding protein that function as a pre-mRNA splicing factor. Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Acts by enhancing the binding of U2AF2 to weak pyrimidine tracts. Also participates in the regulation of alternative pre-mRNA splicing. Activates exon 5 skipping of PTPRC during T cell activation, an event reversed by GFI1. Binds to RNA at the AG dinucleotide at the 3'-splice site.

Poids moléculaire: 22 kDa

ID gène: 199746

UniProt: Q8WU68