WDYHV1 anticorps

N° du produit ABIN7467823

Détail du produit anti-WDYHV1 anticorps

Antigène: WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp WDYHV1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)

Réactivité croisée: Humain, Souris

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human WDYHV1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.58 mg/mL

Buffer: 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur WDYHV1

Antigène: WDYHV1 (WDYHV Motif Containing 1 (WDYHV1))

Autre désignation: WDYHV motif containing 1 (WDYHV1 Produits)

Synonymes: anticorps ntaq1, anticorps C8orf32, anticorps 2410187C16Rik, anticorps AU014961, anticorps AW550036, anticorps Ntaq1, anticorps RGD1311362, anticorps C14H8orf32, anticorps si:rp71-45k5.3, anticorps WDYHV motif containing 1, anticorps WDYHV motif containing 1 S homeolog, anticorps WDYHV1, anticorps wdyhv1.S, anticorps wdyhv1, anticorps Wdyhv1

Sujet: WDYHV motif containing 1 , C8orf32,Mediates the side-chain deamidation of N-terminal glutamine residues to glutamate, an important step in N-end rule pathway of protein degradation. Conversion of the resulting N-terminal glutamine to glutamate renders the protein susceptible to arginylation, polyubiquitination and degradation as specified by the N-end rule. Does not act on substrates with internal or C-terminal glutamine and does not act on non-glutamine residues in any position. Does not deaminate acetylated N-terminal glutamine. With the exception of proline, all tested second-position residues on substrate peptides do not greatly influence the activity. In contrast, a proline at position 2, virtually abolishes deamidation of N-terminal glutamine.

Poids moléculaire: 24 kDa

ID gène: 55093

UniProt: Q96HA8