ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1) (C-Term) anticorps

N° du produit ABIN7468312

L’anticorps anti-ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 Polyclonal Lapin est utilisé pour la détection de ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1) (C-Term) anticorps (ABIN7468312)

Antigène: ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Western Blotting (WB)

Détail du produit

Épitope: C-Term

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the C-terminus region of human EDEM1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: Jurkat membrane extract Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.21 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détail du antigène

Antigène: ER Degradation-Enhancing alpha-Mannosidase-Like Protein 1 (EDEM1)

Autre désignation: ER degradation enhancing alpha-mannosidase like protein 1

Sujet:

Synonyms: ER degradation enhancing alpha-mannosidase like protein 1 , EDEM

Background: Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It lacks mannosidase activity.

Poids moléculaire: 74 kDa

ID gène: 9695

UniProt: Q92611