Protein/nucleic Acid Deglycase DJ-1 (PARK7) (N-Term) anticorps

N° du produit ABIN7468819

L’anticorps anti-Protein/nucleic Acid Deglycase DJ-1 Polyclonal Lapin est utilisé pour la détection de Protein/nucleic Acid Deglycase DJ-1 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour Protein/nucleic Acid Deglycase DJ-1 (PARK7) (N-Term) anticorps (ABIN7468819)

Antigène: Protein/nucleic Acid Deglycase DJ-1 (PARK7)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: KO Validated

Détail du produit

Épitope: N-Term

Réactivité croisée: Humain, Souris, Rat

Purification: Purified by antigen-affinity chromatography.

Immunogène: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Park7 / DJ-1. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:20000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: 293T , A431 , HeLa , HepG2 , U87-MG , SK-N-SH , IMR32 , SK-N-AS Validation: KO/KD

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.2 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détail du antigène

Antigène: Protein/nucleic Acid Deglycase DJ-1 (PARK7)

Autre désignation: Parkinsonism associated deglycase

Sujet:

Synonyms: Parkinsonism associated deglycase , DJ-1 , DJ1 , GATD2 , HEL-S-67p

Background: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

Poids moléculaire: 20 kDa

ID gène: 11315

UniProt: Q99497