Uncoupling Protein 1 anticorps
Aperçu rapide pour Uncoupling Protein 1 anticorps (ABIN7469139)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Réactivité croisée
- Souris
-
Purification
- Affinity purified by Protein A.
-
Immunogène
- Recombinant protein encompassing a sequence within the center region of human UCP1. The exact sequence is proprietary.
-
Isotype
- IgG2a
-
-
-
-
Indications d'application
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1XPBS pH 7, 20 % Glycerol, No Preservative
-
Agent conservateur
- Without preservative
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
- Uncoupling Protein 1
-
Sujet
-
Synonyms: uncoupling protein 1 , SLC25A7 , UCP
Background: Mitochondrial uncoupling proteins (UCP) are members of the family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed only in brown adipose tissue, a specialized tissue which functions to produce heat. [provided by RefSeq]
-
Poids moléculaire
- 33 kDa
-
ID gène
- 7350
-
UniProt
- P25874
Antigène
-
