MBD5 anticorps

N° du produit ABIN7469295

Cet anticorps Lapin Polyclonal détecte spécifiquement MBD5 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour MBD5 anticorps (ABIN7469295)

Antigène: MBD5 (Methyl-CpG Binding Domain Protein 5 (MBD5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MBD5 anticorps

Réactivité croisée: Humain

Purification: Purified by antigen-affinity chromatography.

Immunogène: Recombinant protein encompassing a sequence within the center region of human MBD5. The exact sequence is proprietary.

Isotype: IgG

Information d'application

Indications d'application: WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Commentaires:

Positive Control: HepG2 nuclear extract Validation: Orthogonal

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 2.19 mg/mL

Buffer: 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Détails sur MBD5

Antigène: MBD5 (Methyl-CpG Binding Domain Protein 5 (MBD5))

Autre désignation: MBD5

Sujet:

Synonyms: methyl-CpG binding domain protein 5 , MRD1

Background: This gene encodes a member of the methyl-CpG-binding domain (MBD) family. The MBD consists of about 70 residues and is the minimal region required for a methyl-CpG-binding protein binding specifically to methylated DNA. In addition to the MBD domain, this protein contains a PWWP domain (Pro-Trp-Trp-Pro motif), which consists of 100-150 amino acids and is found in numerous proteins that are involved in cell division, growth and differentiation. Mutations in this gene cause mental retardation autosomal dominant type 1. Haploinsufficiency of this gene is associated with a syndrome involving microcephaly, intellectual disabilities, severe speech impairment, and seizures. Alternatively spliced transcript variants have been found, but their full-length nature is not determined. [provided by RefSeq]

Poids moléculaire: 160 kDa

ID gène: 55777

UniProt: Q9P267

Pathways: Chromatin Binding