Recombinant Hemagglutinin anticorps

N° du produit ABIN7487730

L’anticorps Human Monoclonal anti-Hemagglutinin a été validé pour . Il convient pour détecter Hemagglutinin dans des échantillons de Influenza A Virus.

Aperçu rapide pour Recombinant Hemagglutinin anticorps (ABIN7487730)

Antigène: Hemagglutinin (HA)

Type d'anticorp: Recombinant Antibody

Reactivité: Influenza A Virus

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp Hemagglutinin est non-conjugé

Application: Veuillez nous consulter SVP

Clone: CR6261

Détail du produit anti-Hemagglutinin anticorps

Fonction: Anti-HA [CR6261], Human IgG1, kappa

Specificité: This antibody binds hemaglutinin of most group 1 influenza viruses. CR6261 recognizes a highly conserved helical region in the membrane-proximal stem of HA1/HA2.

Attributs du produit:

Original Species of Ab: Human

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: The original antibody was isolated using phage display from the IgM+ memory B cells of a healthy individual vaccinated against influenza.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The antibody neutralizes the virus by blocking conformational rearrangements associated with membrane fusion. CR6261 neutralizes multiple influenza subtypes, including H1, H2, H5, H6, H8, and H9, and protects mice from lethal challenge with H1N1 and H5N1 viruses when administered up to five days post-infection (PMID: 19251591). It is reported that Oseltamivir/Zanamivir may congruously improve the therapeutic efficacy of CR6261 (PMID: 22693576).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur Hemagglutinin

Antigène: Hemagglutinin (HA)

Autre désignation: Hemagglutinin

Classe de substances: Influenza Protein

Sujet: Hemagglutinin, Avian Influenza Virus, AIV, H1N1, H5N1, Influenza A virus

UniProt: Q9WFX3