Recombinant MAGEA3 anticorps

N° du produit ABIN7487737

Cet anticorps anti-MAGEA3 est un anticorps Human Monoclonal détectant MAGEA3 dans WB, ELISA, IHC, FACS et IP. Adapté pour Humain.

Aperçu rapide pour Recombinant MAGEA3 anticorps (ABIN7487737)

Antigène: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp MAGEA3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: 21B4

Détail du produit anti-MAGEA3 anticorps

Fonction: Anti-MAGEA3 [21B4], Human IgG1, kappa

Specificité: This antibody binds human MAGEA3 and MAGEA6, but does not cross react with other members of the MAGE family like MAGE-A1, MAGE-A4 and MAGE-A10. MAGE-A3 is a tumor specific antigen and it is expressed on many tumors like melanoma, non-small cell lung cancer, hematologic malignancies, and others.

Attributs du produit:

Original Species of Ab: Human

Original Format of Ab: IgG1

Purification: Protein A affinity purified

Immunogène: The original antibody was isolated from a patient suffering from a tumor expressing a tumor specific antigen like MAGE-A3.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The binding specificity of this antibody towards MAGE-A3 was determined using ELISA. The original antibody cross reacts with MAGEA6 but does not react with other members of the MAGE family in an ELISA or western blot assay. This antibody was used in the detection of HEK293T cells expressing MAGEA3 and MAGEA6 using flow cytometry. The original IgG1 antibody was capable of immunoprecipitating MAGE-A3 from lysates of SK-MEL-37 cells endogenously expressing MAGEA3. The original antibody was also used in the immunohistochemical staining of tissues form normal testis and squamous cell carcinoma of the lung (US20140093514).

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: PBS with 0.02 % Proclin 300.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C.

Détails sur MAGEA3

Antigène: MAGEA3 (Melanoma Antigen Family A, 3 (MAGEA3))

Autre désignation: MAGEA3

Sujet: MAGE-3, MAGE3, MAGE 3, CT1.3, MAGE-3 antigen, Melanoma-associated antigen 3, Antigen MZ2-D, Cancer/testis antigen 1.3, MAGEA6, MAGE6, Melanoma-associated antigen 6, Cancer/testis antigen 1.6, CT1.6, MAGE-6 antigen, MAGE3B antigen

UniProt: P43357, P43360