Desmoglein 1 anticorps (AA 51-150)

N° du produit ABIN720520

Cet anticorps Lapin Polyclonal détecte spécifiquement Desmoglein 1 dans ELISA, ICC, IHC (p), IHC (fro), IF (cc) et IF (p). Il présente une réactivité envers Humain.

Aperçu rapide pour Desmoglein 1 anticorps (AA 51-150) (ABIN720520)

Antigène: Desmoglein 1 (DSG1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Desmoglein 1 est non-conjugé

Application: ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Détail du produit anti-Desmoglein 1 anticorps

Épitope: AA 51-150

Homologie: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human Desmoglein 1

Isotype: IgG

Information d'application

Indications d'application: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Date de péremption: 12 months

Détails sur Desmoglein 1

Antigène: Desmoglein 1 (DSG1)

Autre désignation: Desmoglein 1

Sujet:

Synonyms: Cadherin family member 4, CDHF4, Desmoglein-1, Desmosomal Glycoprotein 1, DG1, DGI, DSG, DSG1, DSG1_HUMAN, Pemphigus Foliaceus Antigen, PPKS1, SPPK1.

Background: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1) [MIM:148700], also known as keratosis palmoplantaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.

ID gène: 1828

Pathways: Cell-Cell Junction Organization