Thrombomodulin anticorps

N° du produit ABIN7505855

Cet anticorps anti-Thrombomodulin est un anticorps Souris Monoclonal détectant Thrombomodulin dans FACS. Adapté pour Humain.

Aperçu rapide pour Thrombomodulin anticorps (ABIN7505855)

Antigène: Thrombomodulin (THBD)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Thrombomodulin est non-conjugé

Application: Flow Cytometry (FACS)

Clone: M80

Détail du produit anti-Thrombomodulin anticorps

Fonction: Anti-Hu CD141 Purified

Specificité: The mouse monoclonal antibody M80 recognizes an extracellular epitope of CD141, a 75 kDa transmembrane glycoprotein expressed mainly on macrophages, monocytes, platelets and endothelial cells.

Purification: Purified by protein-A affinity chromatography.

Immunogène: MV4-11 cell line

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1-5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur Thrombomodulin

Antigène: Thrombomodulin (THBD)

Autre désignation: CD141

Sujet: Thrombomodulin,CD141, also known as thrombomodulin or fetomodulin, is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system, but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages, monocytes, a subpopulation of myeloid dendritic cells, on platelets and endothelial cells, but also e.g. on keratinocytes (epithelium). After binding to thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.,Thrombomodulin, fetomodulin, THBD, THRM, THPH12, TM

ID gène: 7056

UniProt: P07204