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Thrombomodulin anticorps

THBD Reactivité: Humain FACS Hôte: Souris Monoclonal M80 unconjugated
N° du produit ABIN7505855
  • Antigène Voir toutes Thrombomodulin (THBD) Anticorps
    Thrombomodulin (THBD)
    Reactivité
    • 120
    • 36
    • 19
    • 3
    • 2
    • 1
    Humain
    Hôte
    • 77
    • 56
    • 6
    • 2
    Souris
    Clonalité
    • 72
    • 69
    Monoclonal
    Conjugué
    • 61
    • 21
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Thrombomodulin est non-conjugé
    Application
    • 97
    • 56
    • 45
    • 43
    • 27
    • 22
    • 21
    • 16
    • 15
    • 14
    • 13
    • 13
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Fonction
    Anti-Hu CD141 Purified
    Specificité
    The mouse monoclonal antibody M80 recognizes an extracellular epitope of CD141, a 75 kDa transmembrane glycoprotein expressed mainly on macrophages, monocytes, platelets and endothelial cells.
    Purification
    Purified by protein-A affinity chromatography.
    Immunogène
    MV4-11 cell line
    Clone
    M80
    Isotype
    IgG1
    Top Product
    Discover our top product THBD Anticorps primaire
  • Indications d'application
    Flow cytometry: Recommended dilution: 1-5 μg/mL
    Restrictions
    For Research Use only
  • Concentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Do not freeze.
  • Antigène
    Thrombomodulin (THBD)
    Autre désignation
    CD141 (THBD Produits)
    Synonymes
    anticorps AHUS6, anticorps BDCA3, anticorps CD141, anticorps THPH12, anticorps THRM, anticorps TM, anticorps AI385582, anticorps THBD, anticorps HAST, anticorps HAST3, anticorps M-PST, anticorps ST1A3/ST1A4, anticorps ST1A5, anticorps STM, anticorps TL-PST, anticorps thrombomodulin, anticorps sulfotransferase family 1A member 3, anticorps THBD, anticorps Thbd, anticorps SULT1A3
    Sujet
    Thrombomodulin,CD141, also known as thrombomodulin or fetomodulin, is a single chain type I transmembrane glycoprotein serving as a receptor for thrombin and as an important cofactor in the protein C anticoagulant system, but it is also involved in embryonic and atherosclerotic plaque development. CD141 is expressed mainly on macrophages, monocytes, a subpopulation of myeloid dendritic cells, on platelets and endothelial cells, but also e.g. on keratinocytes (epithelium). After binding to thrombin, CD141 activates protein C, which degrades clotting factors Va and VIIIa, and as a consequence the amount of thrombin is reduced. Mutations in the CD141 gene can cause a thromboembolic disease known as inherited thrombophilia.,Thrombomodulin, fetomodulin, THBD, THRM, THPH12, TM
    ID gène
    7056
    UniProt
    P07204
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