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CD245 anticorps (PE)

Cet anticorps Souris Monoclonal détecte spécifiquement dans FACS. Il présente une réactivité envers Humain.
N° du produit ABIN7505889

Aperçu rapide pour CD245 anticorps (PE) (ABIN7505889)

Antigène

CD245

Reactivité

Humain

Hôte

  • 3
Souris

Clonalité

  • 3
Monoclonal

Conjugué

  • 2
  • 1
PE

Application

  • 3
  • 2
  • 1
  • 1
Flow Cytometry (FACS)

Clone

DY12
  • Fonction

    Anti-Hu CD245 PE

    Specificité

    The mouse monoclonal antibody DY12 recognizes an extracellular epitope of CD245, a transmembrane protein expressed mainly by peripheral blood lymphocytes, NK cells, monocytes, granulocytes and platelets.

    Purification

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    Immunogène

    human NK-type YT2C2 cells

    Isotype

    IgG1 kappa
  • Indications d'application

    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.

    Restrictions

    For Research Use only
  • Buffer

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène

    CD245

    Sujet

    CD245 is a 220-250 kDa transmembrane protein of unknown structure. It is expressed at lower level on resting blood lymphocytes, granulocytes, platelets, and thymocytes, and at high level on monocytes and on IL-2-dependent T cell lines. It is also expressed on Ewing sarcoma and osteosarcoma cell lines. CD245 seems to act as a costimulation molecule of T and NK cells.,p220/240, DY12, DY35
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