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BTLA anticorps (PE)

BTLA Reactivité: Humain, Non-Human Primate FACS Hôte: Souris Monoclonal MIH26 PE
N° du produit ABIN7505892
  • Antigène Voir toutes BTLA Anticorps
    BTLA (B and T Lymphocyte Associated (BTLA))
    Reactivité
    • 59
    • 35
    • 3
    • 2
    • 1
    • 1
    Humain, Non-Human Primate
    Hôte
    • 33
    • 28
    • 11
    • 4
    • 1
    • 1
    Souris
    Clonalité
    • 44
    • 32
    • 2
    Monoclonal
    Conjugué
    • 45
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp BTLA est conjugé à/à la PE
    Application
    • 50
    • 44
    • 27
    • 13
    • 13
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Flow Cytometry (FACS)
    Fonction
    Anti-Hu CD272 PE
    Specificité
    The mouse monoclonal antibody MIH26 recognizes an extracellular epitope of CD272, a transmembrane glycoprotein serving as a negative regulator of the activation in various leukocyte types.
    Purification
    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
    Immunogène
    cells transfected with human CD272
    Clone
    MIH26
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product BTLA Anticorps primaire
  • Indications d'application
    Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
    Restrictions
    For Research Use only
  • Buffer
    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • Antigène
    BTLA (B and T Lymphocyte Associated (BTLA))
    Autre désignation
    CD272 (BTLA Produits)
    Synonymes
    anticorps BTLA, anticorps BTLA1, anticorps CD272, anticorps A630002H24, anticorps B and T lymphocyte associated, anticorps BTLA, anticorps Btla
    Sujet
    B and T lymphocyte associated,CD272, a type I transmembrane glycoprotein, contains in its intracellular domain two ITIM sequences, which are upon CD272 triggering phosphorylated and recruit SHP phosphatases to attenuate cell activation. CD272 is expressed on B and T lymphocytes, NK cells, dendritic cells, and macrophages, and its ligand is CD270. Defects in CD272-CD270 inhibitory mechanism lead to autoimmune diseases. Overexpression of CD272 is a marker of tolerant T cells.,BTLA1
    ID gène
    151888
    UniProt
    Q7Z6A9
    Pathways
    Cancer Immune Checkpoints
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