L’anticorps anti-SIGLEC9 Monoclonal produit chez le Souris a été validé pour WB, ELISA, FACS, ICC et IP. Il convient pour la détection de SIGLEC9 dans des échantillons provenant de Humain.
}
The mouse monoclonal antibody K8 recognizes an extracellular epitope of CD239, a type I transmembrane glycoprotein expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells.
Sialic acid binding Ig like lectin 9,CD329 is a type I transmembrane glycoprotein of siglec family, which contains intracellular ITIM motif, and a SLAM-like motif, that acts as a docking site for SAP. CD329 can regulate TCR signaling by recruitment of SHP-1, which results in down-regulation of TCR-based gene transcription. It is expressed above all on monocytes, neutrophils, and a minor population of CD16+CD56- cells, weaker expression is detectable in some B cells, NK cells, and T cells.,SIGLEC9