CD52 anticorps
Aperçu rapide pour CD52 anticorps (ABIN7505943)
Antigène
Voir toutes CD52 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD52 Purified
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Specificité
- The mouse monoclonal antibody 4C8 recognizes CD52, a GPI-anchored glycopeptide expressed on the surface of lymphocytes, macrophages, epithelial cells of male reproductive tract, and mature sperms.
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Purification
- Purified by protein-A affinity chromatography.
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Immunogène
- human lymphocytes
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Isotype
- IgG3
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Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- CD52
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Autre désignation
- CD52
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Sujet
- CD52 Molecule,CD52 (CAMPATH-1, HE5) is a highly glycosylated GPI-anchored 21-28 kDa glycopeptide which is present at high levels on lymphocytes, macrophages, epithelial cells of male reproductive tract and mature sperm. Its 12-amino acid beckbone carries a complex N-linked carbohydrate moiety, which differs between sperm and leukocyte CD52, as well as the GPI anchor does. CD52 can be acquired by sperm cells from seminal plasma, where it is released by epithelial cells. Although CD52 is not an essential T-cell costimulator, its triggering results in activation of normal human T cells. CD52 is a very good target for antibody/complement-mediated cell lysis.,CAMPATH-1, HE5, ESPE5
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ID gène
- 1043
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UniProt
- P31358
Antigène
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