Galectin 9 anticorps
Aperçu rapide pour Galectin 9 anticorps (ABIN7505977)
Antigène
Voir toutes Galectin 9 (LGALS9) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu Galectin-9 Purified
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Attributs du produit
- The mouse monoclonal antibody 9M1-3 recognizes an epitope within C terminus of human galectin-9, a glycan-binding protein expressed mainly on activated Th cells and FoxP3+ Treg cells.
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Purification
- Purified by protein-A affinity chromatography.
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Immunogène
- recombinant M-type splicing variant of human galectin 9
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Isotype
- IgG1, kappa
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Indications d'application
- Flow cytometry: Recommended dilution: 1-4 μg/mL. Intracellular staining.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- Galectin 9 (LGALS9) (Lectin, Galactoside-Binding, Soluble, 9 (LGALS9))
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Autre désignation
- Galectin-9
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Sujet
- Galectin 9,Galectin-9 is a glycan-binding protein, which is expressed in three main isoforms of 49 aa, 27 aa, and 15 aa. It can be detected on the cell surface, as well as intracellularly, or in a secreted form. On the cell surface, galectin-9 plays roles in contacts with other cells and with extracellular matrix. It is expressed on multiple cell types, but mainly on Treg cells, activated Th cells and some cancers. Its secreted form acts like a cytokine with immunomodulatory and immunosuppresive functions. Massive and inadequate production of galectin-9, associated with some viral infections or cancers, can counteract immune reactions to these illnesses. High levels of galectin-9 expression lead to poor prognosis of cancer patients.,HUAT, LGalS9A, LEG9
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ID gène
- 3965
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UniProt
- O00182
Antigène
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