SIGLEC10 anticorps (Extracellular Domain)
Aperçu rapide pour SIGLEC10 anticorps (Extracellular Domain) (ABIN7506009)
Antigène
Voir toutes SIGLEC10 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Extracellular Domain
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Fonction
- Anti-Hu SIGLEC10 Purified
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Attributs du produit
- The mouse monoclonal antibody 5G6 recognizes an extracellular epitope of human SIGLEC10, a sialic acid-binding lectin expressed on subsets of human leucocytes.
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Purification
- Purified by protein-A affinity chromatography.
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Immunogène
- SIGLEC10 extracellular domain fused with human IgG1 Fc fragment
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Isotype
- IgG1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- SIGLEC10 (Sialic Acid Binding Ig-Like Lectin 10 (SIGLEC10))
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Autre désignation
- SIGLEC10
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Sujet
- Sialic acid binding Ig like lectin 10,SIGLEC10 is a CD33-related receptor of sialoglycans, expressed on eosinophils, monocytes, a subpopulation of NK cells, and at lower level on B cells. Its murine ortholog is Siglec G. SIGLEC10 seems to act as an immunomodulatory receptor, which binds to VAP-1, a glycoprotein expressed on endothelium under inflammatory conditions. Another ligand of SIGLEC10 is CD24, a marker of poorer prognosis in carcinomas.,PRO940, SGL2
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ID gène
- 89790
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UniProt
- Q96LC7
Antigène
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