Interleukin 17a anticorps
Aperçu rapide pour Interleukin 17a anticorps (ABIN7536930)
Antigène
Voir toutes Interleukin 17a (IL17A) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Purified Anti-Mouse IL-17A Antibody [17F3]
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Purification
- Purified
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Isotype
- IgG1, kappa
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Indications d'application
- Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 μg per 10^6 cells in 100 μL volume or 100 μL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
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Commentaires
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Matching Isotype Control: (ABIN7469768)
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Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Phosphate buffered solution, pH 7.2, containing 0.09 % stabilizer.
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Stock
- 4 °C
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Stockage commentaire
- This product can be stored at 2-8°C for 12 months. Do not freeze.
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Date de péremption
- 12 months
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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Autre désignation
- IL-17A
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Sujet
- IL-17A,Interleukin-17A,Il17a,Ctla9,The 17F3 monoclonal antibody reacts with mouse IL-17A a 15-20 kDa cytokine expressed by Th17 cells, γδ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells. IL-17A has pleiotropic effects in immunoregulation and inflammation. It plays an important role in anti-microbial and chronic inflammation by inducing cytokine and chemokine production, neutrophil influx, and the production of antibacterial peptides but it is also an inflammatory mediator in the development of autoimmune diseases including rheumatoid arthritis, asthma, multiple sclerosis, and psoriasis. The 17F3 antibody has been shown to neutralize IL-18A?in vivo.
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ID gène
- 16171
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UniProt
- Q62386
Antigène
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