L’anticorps Human Monoclonal anti-4-1BB (Utomilumab Biosimilar) a été validé pour ELISA et WB. Il convient pour détecter 4-1BB (Utomilumab Biosimilar) dans des échantillons de Humain.
N° du produit ABIN7538049
Aperçu rapide pour Recombinant 4-1BB (Utomilumab Biosimilar) anticorps (ABIN7538049)
Antigène
4-1BB (Utomilumab Biosimilar)
Type d'anticorp
Recombinant Antibody
Reactivité
Humain
Hôte
Human
Clonalité
Monoclonal
Conjugué
Cet anticorp 4-1BB (Utomilumab Biosimilar) est non-conjugé
Application
ELISA, Western Blotting (WB)
Classe de qualité
Research Grade
Expression System
Mammalian cells
Fonction
Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade
Attributs du produit
Antibody Type: IgG2 kappa
Purification
Recombinant antibody expressed in mammalien cells and purified.
Reactivité: Humain
ELISA, FACS
Hôte: Human
Monoclonal
Biotin
Restrictions
For Research Use only
Buffer
PBS pH 7.5
Stock
4 °C,-20 °C
Stockage commentaire
4°C for short term, -20°C for long term
Antigène
4-1BB (Utomilumab Biosimilar)
Sujet
Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.