Recombinant 4-1BB (Utomilumab Biosimilar) anticorps
Aperçu rapide pour Recombinant 4-1BB (Utomilumab Biosimilar) anticorps (ABIN7538049)
Antigène
Type d'anticorp
Reactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Expression System
- Mammalian cells
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Fonction
- Utomilumab Biosimilar - Anti-Human TNFRSF9 mAb - Research Grade
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Attributs du produit
- Antibody Type: IgG2 kappa
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Purification
- Recombinant antibody expressed in mammalien cells and purified.
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Pureté
- > 85%
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Isotype
- IgG2
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Restrictions
- For Research Use only
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Buffer
- PBS pH 7.5
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- 4°C for short term, -20°C for long term
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- 4-1BB (Utomilumab Biosimilar)
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Sujet
- Utomilumab is a monoclonal antibody that binds to 4-IBB protein (also known as CD137 protein). 4-IBB protein is a receptor found in different immune cells such as helper T-cells, killer T-cells and natural killer cells. 4-IBB/CD137 protein is a costimulatory receptor whose activation results in a series of events that leads to cytokine secretion and effector functions. Hence, targeting CD137 protein has been linked to antitumor immunity response and overall tumor reduction. Indeed, once utomilumab is injected in the bloodstream its specific binding to CD137 protein stimulates the immune cells which, as a result, enhances the immune response against tumors.
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Numéro CAS
- 1417318-27-4
Antigène
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