Recombinant OC126 (Abagovomab Biosimilar) anticorps

N° du produit ABIN7538052

L’anticorps anti-OC126 (Abagovomab Biosimilar) Monoclonal Human est utilisé pour la détection de OC126 (Abagovomab Biosimilar) dans des échantillons de Souris. Il a été validé pour ELISA et WB.

Aperçu rapide pour Recombinant OC126 (Abagovomab Biosimilar) anticorps (ABIN7538052)

Antigène: OC126 (Abagovomab Biosimilar)

Type d'anticorp: Recombinant Antibody

Reactivité: Souris

Hôte: Human

Clonalité: Monoclonal

Conjugué: Cet anticorp OC126 (Abagovomab Biosimilar) est non-conjugé

Application: ELISA, Western Blotting (WB)

Classe de qualité: Research Grade

Détail du produit anti-OC126 (Abagovomab Biosimilar) anticorps

Expression System: Mammalian cells

Fonction: Abagovomab Biosimilar - Anti-idiotope of anti-Mus musculus monoclonal antibody OC126 mAb - Research Grade

Attributs du produit: Antibody Type: idiotypic IgG1-kappa

Purification: Recombinant antibody expressed in mammalien cells and purified.

Pureté: > 85%

Isotype: IgG1 kappa

Information d'application

Restrictions: For Research Use only

Stockage

Buffer: PBS buffer PH7.5

Stock: -80 °C

Stockage commentaire: store at -80°C

Détails sur OC126 (Abagovomab Biosimilar)

Antigène: OC126 (Abagovomab Biosimilar)

Classe de substances: Biosimilar

Sujet: Abagovomab is a murine monoclonal anti-idiotypic antibody (MW: 165-175 kDa), produced by a mouse hybridoma and generated against OC125, which serves to functionally imitate the human cancer antigen 125 (CA-125). Abagovomab has been developed by the pharmaceutical company Menarini for the treatment of ovarian cancer. It (ab2) shows high affinity for the paratope of ab1, and binding of ab2 to Ab1 is almost completely inhibited (93%) by the nominal antigen. The administration of F(ab')2 fragments of abagovomab to rats produces anti-CA-125 immunity with the production of IgG and IgM anti-anti-idiotypic antibodies (ab3) that bind both to abagovomab and CA-125. Non-MHC restricted cell-mediated cytotoxicity for NIH OVCAR3 cell lines is also demonstrated.

Numéro CAS: 792921-10-9