PKD1 anticorps (AA 3682-3873)
Aperçu rapide pour PKD1 anticorps (AA 3682-3873) (ABIN7539645)
Antigène
Voir toutes PKD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 3682-3873
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Fonction
- PKD1 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of mouse PKD1 (AA: 3682-3873) expressed in E. Coli.
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Isotype
- IgG1
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anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 651-876) antibody
PKD1 Reactivité: Humain IHC, WB Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 615-753) antibodyPKD1 Reactivité: Humain IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 131-230) antibodyPKD1 Reactivité: Humain, Souris ELISA, WB, FACS, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (AA 349-612) antibodyPKD1 Reactivité: Souris IHC, WB, ICC, IP Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer910) antibodyPKD1 Reactivité: Humain, Souris, Rat ELISA, WB Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (pSer205) antibodyPKD1 Reactivité: Humain, Souris, Rat IHC, ELISA, WB Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr266), (Thr312) antibodyPKD1 Reactivité: Humain, Souris, Rat IHC, ELISA, WB, IF Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr310) antibodyPKD1 Reactivité: Humain, Souris, Rat IHC, ELISA, WB Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr312) antibodyPKD1 Reactivité: Humain, Souris, Rat IHC, ELISA, WB Hôte: Lapin Polyclonal unconjugated
anti-Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1) (Thr266), (Thr312) antibodyPKD1 Reactivité: Humain, Souris, Rat IHC, ELISA, WB, IF Hôte: Lapin Polyclonal unconjugated
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))
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Autre désignation
- PKD1
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Sujet
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Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate.
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Poids moléculaire
- 466 kDa
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ID gène
- 18763
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UniProt
- O08852
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Pathways
- Myometrial Relaxation and Contraction, Maintenance of Protein Location
Antigène
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