PKD1 anticorps (AA 3682-3873)

N° du produit ABIN7539645

Cet anticorps Rat Monoclonal détecte spécifiquement PKD1 dans ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PKD1 anticorps (AA 3682-3873) (ABIN7539645)

Antigène: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp PKD1 est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 8C3D11

Détail du produit anti-PKD1 anticorps

Épitope: AA 3682-3873

Fonction: PKD1 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of mouse PKD1 (AA: 3682-3873) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PKD1

Antigène: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Autre désignation: PKD1

Sujet: Involved in renal tubulogenesis. Involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. Acts as a regulator of cilium length, together with PKD2. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. May be an ion-channel regulator. Involved in adhesive protein-protein and protein-carbohydrate.

Poids moléculaire: 466 kDa

ID gène: 18763

UniProt: O08852

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location