CD160 anticorps (AA 25-155)

N° du produit ABIN7539709

L’anticorps Souris Monoclonal anti-CD160 a été validé pour FACS et ELISA. Il convient pour détecter CD160 dans des échantillons de Humain.

Aperçu rapide pour CD160 anticorps (AA 25-155) (ABIN7539709)

Antigène: CD160

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD160 est non-conjugé

Application: Flow Cytometry (FACS), ELISA

Clone: 1D4A4

Détail du produit anti-CD160 anticorps

Épitope: AA 25-155

Fonction: CD160 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human CD160 (AA: 25-155) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur CD160

Antigène: CD160

Autre désignation: CD160

Sujet: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 Molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.

Poids moléculaire: 19.8 kDa

ID gène: 11126

UniProt: O95971