DCLK2 anticorps (AA 652-766)

N° du produit ABIN7539736

L’anticorps Souris Monoclonal anti-DCLK2 a été validé pour ELISA, IHC et FACS. Il convient pour détecter DCLK2 dans des échantillons de Humain.

Aperçu rapide pour DCLK2 anticorps (AA 652-766) (ABIN7539736)

Antigène: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp DCLK2 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Clone: 3H1G4

Détail du produit anti-DCLK2 anticorps

Épitope: AA 652-766

Fonction: DCLK2 Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human DCLK2 (AA: 652-766) expressed in mammalian.

Isotype: IgG2a

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur DCLK2

Antigène: DCLK2 (Doublecortin-Like Kinase 2 (DCLK2))

Autre désignation: DCLK2

Sujet: This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified.

Poids moléculaire: 83.6 kDa

ID gène: 166614

UniProt: Q8N568