ICAM2 anticorps (FITC)

N° du produit ABIN7540412

Cet anticorps Souris Monoclonal détecte spécifiquement ICAM2 dans FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour ICAM2 anticorps (FITC) (ABIN7540412)

Antigène: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ICAM2 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Clone: CBR-IC2-2

Détail du produit anti-ICAM2 anticorps (FITC)

Fonction: Anti-Hu CD102 FITC

Specificité: The mouse monoclonal antibody CBR-IC2/2 recognizes an extracellular epitope of CD102 (ICAM-2), an approximately 55 kDa type I transmembrane glycoprotein expressed mainly on vascular endothelial cells and folicular dendritic cells, in lower amount on lymphocytes, monocytes and platelets.

Purification: Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Human CD102 cDNA transfected COS cells

Isotype: IgG2a

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 4 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (0.4 ml) is sufficient for 100 tests.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur ICAM2

Antigène: ICAM2 (Intercellular Adhesion Molecule 2 (ICAM2))

Autre désignation: CD102

Sujet:

NCBI Full Gene Name: intercellular adhesion molecule 2

Description: CD102 / ICAM-2 (intracellular cell adhesion molecule-2), a counter receptor of LFA-1 (CD11a/CD18), is a transmembrane glycoprotein with two extracellular IgC-like domains and intracellular C-terminal tail. It is involved in lymphocyte recirculation and homing to the sites of inflammation. Through interaction with integrins it provides to the immune cells costimulatory signals. Expression of CD102 on blood cells (lymphocytes, monocytes, thrombocytes) is lower than on endothelium and follicular dendritic cells. CD102 levels are upregulated in lymph nodes with malignant infiltration.

Other names: ICAM2

Gene name: ICAM2

ID gène: 3384

UniProt: P13598