CD207 anticorps (PE)

N° du produit ABIN7540425

L’anticorps Souris Monoclonal anti-CD207 a été validé pour FACS. Il convient pour détecter CD207 dans des échantillons de Humain et Non-Human Primate.

Aperçu rapide pour CD207 anticorps (PE) (ABIN7540425)

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Reactivité: Humain, Non-Human Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD207 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Clone: 2G3

Détail du produit anti-CD207 anticorps (PE)

Fonction: Anti-Hu CD207 PE

Specificité: The mouse monoclonal antibody 2G3 recognizes an extracellular/luminal epitope of CD207, a transmembrane protein selectively expressed by Langerhans cells and by some other dendritic cell subsets. This antibody clone can target vaccine-peptides to dendritic cells.

Purification: Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

Immunogène: Fusion protein of human CD207 extracellular part and IgG Fc fragment

Isotype: IgG1 lambda

Information d'application

Indications d'application: Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 10⁶ cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests. Extracellular and intracellular staining.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

Détails sur CD207

Antigène: CD207 (CD207 Molecule, Langerin (CD207))

Autre désignation: CD207

Sujet:

NCBI Full Gene Name: CD207 Molecule

Description: CD207 is a 40 kDa type II transmembrane glycoprotein of the C-type lectin family. It binds to mannose-bearing glycoproteins and glycolipids of microbial and viral antigens, including HIV gp120. CD207 is expressed only in Langerhans cells, which are immature dendritic cells of the epidermis and mucosa, and its expression decreases during Langerhans cells maturation. Upon antigen binding CD207 localizes to the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed membranes, which leads to a nonclassical antigen-processing pathway.

Other names: CLEC4K, langerin

Gene name: CD207

ID gène: 50489

UniProt: Q9UJ71