ITGA5 anticorps (PE)
Aperçu rapide pour ITGA5 anticorps (PE) (ABIN7540446)
Antigène
Voir toutes ITGA5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD49e PE
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Specificité
- The mouse monoclonal antibody SAM1 recognizes an extracellular epitope of CD49e (integrin 5 alpha), a transmembrane glycoprotein expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells.
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Purification
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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Immunogène
- U937 cells
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Isotype
- IgG2b
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Indications d'application
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- ITGA5 (Integrin, alpha 5 (ITGA5))
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Autre désignation
- CD49e
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Sujet
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NCBI Full Gene Name: integrin subunit alpha 5
Description: CD49e (VLA5 alpha) is a type I transmembrane glycoprotein of the integrin alpha subclass (intergrin 5 alpha), expressed on thymocytes, early and activated B cells, monocytes, NK cells, dendritic cells, osteoblast and endothelial cells. It binds to RGD sequence in fibronectin and to neural adhesion molecule L1. CD49e interactions are important for maintaining the integrity of the endothelial monolayer, as well as it is involved in monocyte migration, T cell costimulation, regulation of cell survival, and other.
Other names: VLA5 alpha, integrin 5 alpha, FNRA
Gene name: ITGA5
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ID gène
- 3678
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UniProt
- P08648
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Pathways
- Integrin Complex
Antigène
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