ALDH1L1 anticorps (Internal Region)

N° du produit ABIN7540557

N° du produit (Fournisseur): 600-101-hb6

L’anticorps Chèvre Polyclonal anti-ALDH1L1 a été validé pour WB, IHC, IF, ELISA et FM. Il convient pour détecter ALDH1L1 dans des échantillons de Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour ALDH1L1 anticorps (Internal Region) (ABIN7540557)

Antigène: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Reactivité: Souris

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp ALDH1L1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Fluorescence Microscopy (FM)

Détail du produit anti-ALDH1L1 anticorps

Épitope: Internal Region

N° du produit (Fournisseur): 600-101-hb6

Fournisseur: Rockland

Fonction: Aldh1l1 Antibody

Réactivité croisée (Details): This affinity purified antibody is directed against mouse Aldh1l1.

Purification: The product was affinity purified from monospecific antiserum by immunoaffinity purification.

Stérilité: Sterile filtered

Immunogène: Anti-Aldh1l1 antibody was prepared from whole goat serum produced by repeated immunizations with a synthetic peptide corresponding to an internal portion of mouse Aldh1l1 conjugated to Keyhole Limpet Hemocyanin (KLH).

Isotype: IgG

Information d'application

Indications d'application:

ELISA_Dilution: 1:10,000-1:50,000

Immunohistochemistry_Dilution: 1:200

IF_Microscopy_Dilution: 15 μg/mL

Western_Blot_Dilution: 1:1000

Commentaires:

Anti-Aldh1l1 Antibody has been tested in WB, IHC, and IF.  Expect a band at ~98.7kDa in western blot using appropriate lysates.  Positive control used: NIH3T3 and Ms Liver for WB, Ms Liver and Kidney for IHC, and NIH3T3 for IF.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer:

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

Stabilizer: None

Preservative: 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.

Date de péremption: 12 months

Références pour anticorps anti-ALDH1L1 (ABIN7540557)

Williamson, Fuertes, Dunn, Drew, Jones: "Reactive astrocytes facilitate vascular repair and remodeling after stroke." dans: Cell reports, Vol. 35, Issue 4, pp. 109048, (2022) (PubMed).

Hirai, Miwa, Tanaka, Toriumi, Kunii, Shimbo, Sakamoto, Hino, Izumi, Nagaoka, Yabe, Nakamachi, Shioda, Dan, Miyata, Nishito, Suzuki, Miyashita, Tomoda, Hikida, Horiuchi, Itokawa, Arai, Okado: "High-sucrose diets contribute to brain angiopathy with impaired glucose uptake and psychosis-related higher brain dysfunctions in mice." dans: Science advances, Vol. 7, Issue 46, pp. eabl6077, (2021) (PubMed).

Détails sur ALDH1L1

Antigène: ALDH1L1 (Aldehyde Dehydrogenase 1 Family, Member L1 (ALDH1L1))

Autre désignation: Aldh1l1

Sujet: Goat Anti-Aldh1l1 Antibody, Cytosolic 10-formyltetrahydrofolate dehydrogenase, 10-FTHFDH, FDH, Aldehyde dehydrogenase family 1 member L1, Fthfd,Aldh1l1, also known as Aldehyde Dehydrogenase 1 Family Member L1, belongs to the aldehyde dehydrogenase family.  This protein catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide.  Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. Aldh1l1 is cytoplasmic. Diseases associated with ALDH1L1 include Methanol Poisoning and Pilocytic Astrocytoma.  Anti-Aldh1l1 Antibody is useful for researchers interested in Apoptosis Research, Metabolism Research, and Cancer research.

ID gène: 107747

NCBI Accession: NP_081682

UniProt: Q8R0Y6